The University of Gothenburg intend to purchase an instrument that will be used for measurements of binding kinetics of small-molecule ligands towards biological membranes and proteins. The department of Pharmacology is investigating drug distribution processes and the immediate focus is to quantify binding kinetics (on- and off-rates) and binding affinities of ligands towards immobilised cellular membranes. In this context we study series of tens-to-thousands of small-molecule ligands, and a setup is necessary in which crude cell homogenates or similar cell membrane preparations are immobilised on the sensor surface, and sets of multiple ligands are screened through addition as solutions in aqueous buffer, typically supplemented with dimethyl sulfoxide (DMSO).
Sista ansökningsdag
Tidsfristen för mottagande av anbud var 2021-01-21.
Upphandlingen offentliggjordes den 2020-12-22.
Leverantörer
Följande leverantörer nämns i tilldelningsbeslut eller andra upphandlingsdokument:
Objekt Upphandlingens omfattning
Titel: Instrumentation for Drug Binding Kinetics
EUI 20 061
Produkter/tjänster: Laboratorieutrustning, optisk utrustning och precisionsutrustning (exkl. glas)📦
Kort beskrivning:
“The University of Gothenburg intend to purchase an instrument that will be used for measurements of binding kinetics of small-molecule ligands towards...”
Kort beskrivning
The University of Gothenburg intend to purchase an instrument that will be used for measurements of binding kinetics of small-molecule ligands towards biological membranes and proteins. The department of Pharmacology is investigating drug distribution processes and the immediate focus is to quantify binding kinetics (on- and off-rates) and binding affinities of ligands towards immobilised cellular membranes. In this context we study series of tens-to-thousands of small-molecule ligands, and a setup is necessary in which crude cell homogenates or similar cell membrane preparations are immobilised on the sensor surface, and sets of multiple ligands are screened through addition as solutions in aqueous buffer, typically supplemented with dimethyl sulfoxide (DMSO).
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Ytterligare produkter/tjänster: Medicinsk utrustning, läkemedel och hygienartiklar📦
Plats för genomförandet: Västra Götalands län🏙️
Huvudort eller plats för utförandet: Göteborg.
Beskrivning av upphandlingen:
“The instrument will be used for measurements of binding kinetics of small-molecule ligands towards biological membranes and/or proteins. We are...”
Beskrivning av upphandlingen
The instrument will be used for measurements of binding kinetics of small-molecule ligands towards biological membranes and/or proteins. We are investigating drug distribution processes and the immediate focus of the research to be conducted using the instrument is to quantify binding kinetics (on- and off-rates) and binding affinities of ligands towards immobilised cellular membranes.
About the purchase
The University of Gothenburg intend to purchase an instrument that will be used for measurements of binding kinetics of small-molecule ligands towards biological membranes and proteins. The department of Pharmacology is investigating drug distribution processes and the immediate focus of the research to be conducted using the instrument is to quantify binding kinetics (on- and off-rates) and binding affinities of ligands towards immobilised cellular membranes. In this context we study series of tens-to-thousands of small-molecule ligands, and a setup is necessary in which crude cell homogenates or similar cell membrane preparations are immobilised on the sensor surface, and sets of multiple ligands are screened through addition as solutions in aqueous buffer, typically supplemented with dimethyl sulfoxide (DMSO). Additionally, the instrument will be used to measure binding kinetics and affinities of small molecule ligands (such as pharmaceutical drugs and/or fragments) towards immobilised target proteins (including membrane-bound proteins).
Visa mer Kriterier för tilldelning
Priset är inte det enda tilldelningskriteriet och alla kriterier anges endast i upphandlingsdokumenten
Varaktighet
Slutdatum: 2021-03-22 📅
Information om alternativen
Alternativ ✅
Beskrivning av alternativen: Defined in the procurement documents, section 3.
Förfarande Typ av förfarande
Öppet förfarande
Administrativ information
Tidsfrist för mottagande av anbud eller begäran om deltagande: 2021-01-21
23:59 📅
Språk på vilka anbud eller ansökningar om deltagande kan lämnas in: svenska 🗣️
Språk på vilka anbud eller ansökningar om deltagande kan lämnas in: engelska 🗣️
Anbudet skall vara giltigt till och med: 2021-04-22 📅
Villkor för öppnande av anbud: 2021-01-22
00:00 📅
Kompletterande information Ytterligare information
Visma notice: https://opic.com/id/afopnchefa Granskningsorgan
Namn: Förvaltningsrätten Sverige
Postort: Göteborg
Land: Sverige 🇸🇪
Källa: OJS 2020/S 251-628180 (2020-12-22)
Ytterligare upplysningar (2020-12-29) Upphandlande myndighet Namn och adresser
Namn: Göteborgs universitet
Objekt Upphandlingens omfattning
Kort beskrivning:
“The University of Gothenburg intend to purchase an instrument that will be used for measurements of binding kinetics of small-molecule ligands towards...”
Kort beskrivning
The University of Gothenburg intend to purchase an instrument that will be used for measurements of binding kinetics of small-molecule ligands towards biological membranes and proteins. The department of Pharmacology is investigating drug distribution processes and the immediate focus is to quantify binding kinetics (on- and off-rates) and binding affinities of ligands towards immobilized cellular membranes. In this context we study series of tens-to-thousands of small-molecule ligands, and a setup is necessary in which crude cell homogenates or similar cell membrane preparations are immobilized on the sensor surface, and sets of multiple ligands are screened through addition as solutions in aqueous buffer, typically supplemented with dimethyl sulfoxide (DMSO).
Kompletterande information Ursprunglig referens till meddelandet
Nummer på meddelandet i EUT S: 2020/S 251-628180
Ändringar Text som skall rättas i det ursprungliga meddelandet
Avsnittets nummer: IV.2.2)
Plats för den text som ska ändras: Time limit for receipt of tenders or requests to participate
Gammalt värde
Datum: 2021-01-21 📅
Tid: 23:59
Nytt värde
Datum: 2021-01-25 📅
Tid: 23:59
Text som skall rättas i det ursprungliga meddelandet
Avsnittets nummer: IV.2.6)
Plats för den text som ska ändras:
“Minimum time frame during which the tenderer must maintain the tender, Tender must be valid until” Gammalt värde
Datum: 2021-04-22 📅
Nytt värde
Datum: 2021-04-23 📅
Text som skall rättas i det ursprungliga meddelandet
Avsnittets nummer: IV.2.7)
Plats för den text som ska ändras: Conditions for opening of tenders
Gammalt värde
Datum: 2021-01-22 📅
Tid: 00:00
Nytt värde
Datum: 2021-01-26 📅
Tid: 00:00
Annan kompletterande information
Visma notice: https://opic.com/id/afiwwdoedz
Källa: OJS 2020/S 255-640989 (2020-12-29)
Meddelande om tilldelning (2021-02-24) Objekt Upphandlingens omfattning
Upphandlingens totala värde (exklusive moms): EUR 200 000 💰
Beskrivning
Beskrivning av upphandlingen:
“The instrument will be used for measurements of binding kinetics of small-molecule ligands towards biological membranes and/or proteins. We are...”
Beskrivning av upphandlingen
The instrument will be used for measurements of binding kinetics of small-molecule ligands towards biological membranes and/or proteins. We are investigating drug distribution processes and the immediate focus of the research to be conducted using the instrument is to quantify binding kinetics (on- and off-rates) and binding affinities of ligands towards immobilized cellular membranes.
About the purchase
The University of Gothenburg intend to purchase an instrument that will be used for measurements of binding kinetics of small-molecule ligands towards biological membranes and proteins. The department of Pharmacology is investigating drug distribution processes and the immediate focus of the research to be conducted using the instrument is to quantify binding kinetics (on- and off-rates) and binding affinities of ligands towards immobilized cellular membranes. In this context we study series of tens-to-thousands of small-molecule ligands, and a setup is necessary in which crude cell homogenates or similar cell membrane preparations are immobilized on the sensor surface, and sets of multiple ligands are screened through addition as solutions in aqueous buffer, typically supplemented with dimethyl sulfoxide (DMSO). Additionally, the instrument will be used to measure binding kinetics and –affinities of small molecule ligands (such as pharmaceutical drugs and/or fragments) towards immobilized target proteins (including membrane-bound proteins).
Förfarande Administrativ information
Tidigare publikation om detta förfarande: 2020/S 251-628180
Tilldelning av kontrakt
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Datum för ingående av avtalet: 2021-02-04 📅
Information om anbud
Antal mottagna anbud: 2
Entreprenörens namn och adress
Namn: Creoptix AG
Nationellt registreringsnummer: 114770731
Postadress: zugerstrasse 78
Postort: Wadenswill
Postnummer: 78
Land: Schweiz 🇨🇭
E-post: mwalton@creoptix.com📧
Region: Schweiz/Suisse/Svizzera 🏙️
URL: http://WWW.CREOPTIX.COM🌏
Entreprenören är ett litet eller medelstort företag ✅ Uppgifter om kontraktets/partiets värde (exklusive moms)
Uppskattat totalt värde på kontraktet/lotten: EUR 200 000 💰
Kontraktets/lottens totala värde: EUR 200 000 💰
Kompletterande information Ytterligare information
Visma notice: https://opic.com/id/afgjzpzhld
Källa: OJS 2021/S 041-102358 (2021-02-24)