Service for scaling up a chemical substance

Karolinska Institutet

Invitation to tender
Karolinska Institutet, hereinafter called KI, invites companies, hereinafter called Tenderers, to submit tenders concerning pharmaceutical development through scale-up and manufacture of a chemical substance, a small molecule anti-cancer compound, according to GMP requirements.
Background to the procurement
Prof Thomas Helleday, The Department of Oncology and Pathology, has recently discovered a highly potent small inhibitor of MTHFD2 which shows promise in several cancer models in cells and rodents. The next step is to take this inhibitor through GLP toxicology studies and IND filing before entering first-time-in man studies.
To do this The Helleday Lab wish to procure the active pharmaceutical ingredient (API) from a contract manufacturing organization, that has certified regulatory experience in the GMP synthesis of highly potent compounds.
Agreement term
KI has intention to sign a contract with one (1) supplier.
The agreement period is (4) years.

Sista ansökningsdag

Tidsfristen för mottagande av anbud var 2021-11-22. Upphandlingen offentliggjordes den 2021-10-21.

Vem? Vad? Var?
Upphandlingshistorik
Datum Dokument
2021-10-21 Meddelande om upphandling
2021-10-28 Ytterligare upplysningar
2021-12-09 Meddelande om tilldelning
Meddelande om upphandling (2021-10-21)
Objekt
Upphandlingens omfattning
Titel: Tjänster tillhandahållna av medicinska laboratorier
Referensnummer: 2-4324/2021
Kort beskrivning:
Invitation to tender Karolinska Institutet, hereinafter called KI, invites companies, hereinafter called Tenderers, to submit tenders concerning pharmaceutical development through scale-up and manufacture of a chemical substance, a small molecule anti-cancer compound, according to GMP requirements. Background to the procurement Prof Thomas Helleday, The Department of Oncology and Pathology, has recently discovered a highly potent small inhibitor of MTHFD2 which shows promise in several cancer models in cells and rodents. The next step is to take this inhibitor through GLP toxicology studies and IND filing before entering first-time-in man studies. To do this The Helleday Lab wish to procure the active pharmaceutical ingredient (API) from a contract manufacturing organization, that has certified regulatory experience in the GMP synthesis of highly potent compounds. Agreement term KI has intention to sign a contract with one (1) supplier. The agreement period is (4) years.
Visa mer
Meddelandeinformation
Originalspråk: engelska 🗣️
Dokumenttyp: Meddelande om upphandling
Kontraktets art: Tjänster
Reglering: Europeiska unionen – inom ramen för avtalet om offentlig upphandling
Gemensam upphandlingsterminologi (CPV)
Kod: Tjänster tillhandahållna av medicinska laboratorier 📦
Plats för genomförandet
NUTS-region: Stockholm 🏙️

Förfarande
Förfarandetyp: Öppet förfarande
Anbudstyp: Anbud på alla delar
Kriterier för tilldelning
Det ekonomiskt mest fördelaktiga

Upphandlande myndighet
Identitet
Land: Sverige 🇸🇪
Upphandlande myndighet (typ): Ministerium eller annan central
Upphandlande myndighet (namn): Karolinska Institutet
Postadress: Universitetsförvaltningen
Postnummer: 171 77
Postort: Stockholm
Kontakt
Webbadress: http://www.ki.se 🌏
E-post: hanna.glad@ki.se 📧
URL för dokument: https://tendsign.com/doc.aspx?UniqueId=afhktscbbh&GoTo=Docs 🌏
URL för deltagande: https://tendsign.com/doc.aspx?UniqueId=afhktscbbh&GoTo=Tender 🌏

Referens
Datum
Avsändningsdatum: 2021-10-21 📅
Sista anbudsdag: 2021-11-22 📅
Publiceringsdatum: 2021-10-26 📅
Startdatum: 2022-01-01 📅
Slutdatum: 2024-12-31 📅
Identifierare
Meddelandenummer: 2021/S 208-544571
EUT-S-nummer: 208
Ytterligare information
Mercell notice: https://opic.com/id/afhktscbbh

Objekt
Upphandlingens omfattning
Kort beskrivning:
Invitation to tender
Karolinska Institutet, hereinafter called KI, invites companies, hereinafter called Tenderers, to submit tenders concerning pharmaceutical development through scale-up and manufacture of a chemical substance, a small molecule anti-cancer compound, according to GMP requirements.
Visa mer
Background to the procurement
Prof Thomas Helleday, The Department of Oncology and Pathology, has recently discovered a highly potent small inhibitor of MTHFD2 which shows promise in several cancer models in cells and rodents. The next step is to take this inhibitor through GLP toxicology studies and IND filing before entering first-time-in man studies.
Visa mer
To do this The Helleday Lab wish to procure the active pharmaceutical ingredient (API) from a contract manufacturing organization, that has certified regulatory experience in the GMP synthesis of highly potent compounds.
Agreement term
KI has intention to sign a contract with one (1) supplier.
The agreement period is (4) years.
The contract will be used by the Department of Oncology and Pathology, Karolinska Institutet (KI), Solna.
Karolinska Institutet, KI
Karolinska Institutet ("KI") is one of the world’s foremost medical universities. Our vision is to advance knowledge about life and strive towards better health for all.
As a university, KI is Sweden’s single largest centre of medical academic research and offers the country’s widest range of medical courses and programmes.
Since 1901 the Nobel Assembly at Karolinska Institutet has selected the Nobel laureates in Physiology or Medicine.
For additional information, please visit www.ki.se.
The agreement shall become effective when the parties, KI and the chosen supplier, have signed the contract. The exact start date shall be determined upon signing of the agreement.
Contents
The tender request documentation consists of the following document parts:1. Invitation to tender2. Administrative rules3. Evaluation and qualification4. Supplier qualification5. Technical requirements6. Commercial terms and conditionsAdditional information published during the procurement procedure is considered to be part of the procurement documents.The Tenderer is responsible for acquiring all of the procurement documents.
Visa mer
Procurement authority
Karolinska InstitutetReg. no: 202100-2973Visiting address:Nobels väg 5SE-171 77 Stockholm
Contact person during the procurement process
Any questions are to be asked via TendSign.
Contact person from purchasing and Procurement unit: Hanna Glad E-mail: hanna.glad@ki.se
Contact person from the department: Martin ScobieE-mail: martin.scobie@ki.se
Procurement procedure
The procurement is carried out as an Open procedure according to the Swedish Public Procurement Act (2016:1145) (LOU).
For more information concerning procurement procedures, please refer to http://www.upphandlingsmyndigheten.se/en/publicprocurement/.
Tender’s period of validity
The tender must be valid until 2022-03-04.
If necessary, KI may request an extension of the tender validity period, for example, if the procurement process or the contract award decision is appealed in court.
Compensation
KI shall reject all Tenderer’s claims for compensation for the work performed during participation in the procurement process.
Beskrivning av förnyelser: 2 extensions per 12 months

Förfarande
Rättslig grund: 32014L0024
Tidpunkt för mottagande av anbud: 23:59
Språk på vilka anbud eller ansökningar om deltagande kan lämnas in: engelska 🗣️
Anbudens giltighetstid: 2022-03-04 📅
Datum för öppnande av anbud: 2021-11-23 📅
Tidpunkt för öppnande av anbud: 00:00

Upphandlande myndighet
Identitet
Nationellt registreringsnummer: 202100-2973
Kontakt
Kontaktpunkt: Hanna Glad
URL för dokument: https://tendsign.com/doc.aspx?UniqueId=afhktscbbh&GoTo=Docs 🌏

Kompletterande information
Granskningsorgan
Namn: Förvaltningsrätten
Postort: Stockholm
Land: Sverige 🇸🇪
Källa: OJS 2021/S 208-544571 (2021-10-21)
Ytterligare upplysningar (2021-10-28)
Objekt
Meddelandeinformation
Dokumenttyp: Ytterligare upplysningar

Referens
Datum
Avsändningsdatum: 2021-10-28 📅
Publiceringsdatum: 2021-11-02 📅
Identifierare
Meddelandenummer: 2021/S 212-559961
Refererar till meddelande: 2021/S 208-544571
EUT-S-nummer: 212
Ytterligare information
Mercell notice: https://opic.com/id/afudrbwght
Källa: OJS 2021/S 212-559961 (2021-10-28)
Meddelande om tilldelning (2021-12-09)
Objekt
Meddelandeinformation
Dokumenttyp: Meddelande om tilldelning

Förfarande
Anbudstyp: Ej tillämpligt
Kriterier för tilldelning
Lägsta pris

Referens
Datum
Avsändningsdatum: 2021-12-09 📅
Publiceringsdatum: 2021-12-14 📅
Identifierare
Meddelandenummer: 2021/S 242-638393
EUT-S-nummer: 242
Ytterligare information
Motivation for cancelling When examining and evaluating tenders, it emerged that all tenders contain errors or/and are irrelevant to the contract with regard to the budget for the procurement. The dificiency cannot be cured by clarifications from the tenderer. When no suitable tenders remain, the procurement is cancelled. Mercell notice: https://opic.com/id/afkywbzkjj
Visa mer
Motivation for cancelling
When examining and evaluating tenders, it emerged that all tenders contain errors or/and are irrelevant to the contract with regard to the budget for the procurement. The dificiency cannot be cured by clarifications from the tenderer.
When no suitable tenders remain, the procurement is cancelled.
Källa: OJS 2021/S 242-638393 (2021-12-09)
Nya upphandlingar inom relaterade kategorier 🆕
Relaterade sökningar 🔍
Region:
Sverige Östra Sverige Stockholm
Produkter/tjänster:
Hälso- och sjukvård samt socialvård Hälsovårdstjänster Diverse hälsovård Tjänster tillhandahållna av medicinska...